|
Criteria of inclusion and exclusion of patients. |
|
| Inclusion criteria |
Exclusion criteria |
|
|
|
| patients meeting all of the following criteria are considered for inclusion in the study: |
patients with any of the following will not be included in the trial: |
| - scheduled for elective major partial liver resection of ≥3 liver segments for liver neoplasms |
- patients <18 and >90 years |
| - written informed consent |
- patients <50 and >120 kg |
| - adequate contraception is required for women with childbearing potential |
- patients with severe, organ-specific disorders (e.g., liver or renal failure, acute pancreatitis) |
| - patients undergoing emergency procedures |
|
| - patients with expected intubation problems |
|
| - pregnancy and/or lactation |
|
| - history of hypersensitivity to the investigational product or to any drug with similar chemical structure or to any compound present in the pharmaceutical form of the investigational product |
|
| - simultaneous participation in another clinical trial |
|
| - mental condition rendering the subject incapable of understanding the nature, scope, and consequences of the trial |
|
| No subject will be enrolled in this study more than once. |
|
Schemmer et al. BMC Surgery 2008 8:2 doi:10.1186/1471-2482-8-2 |
|