Table 5

Best cut-off values, specifity, sensitivity, and areas under the curve (AUC) with 95 % confidence intervals estimated for CRP, IL-6 and WBC. Significantly best parameters are shown bold with italic p values in comparison to WBC.

Criterion

Sensitivity

95% CI

Specificity

95% CI

AUC

sign.

95% CI


1 vs. 4

WBC

>14.3

80

51.9 – 95.4

62.5

24.7 – 91.0

0.667

n.s.

0.442 – 0.847

IL-6

>12.2

93.3

68.0 – 98.9

100

62.9 – 100.0

0.992

<.005

0.836 – 1.000

CRP

>11

86.7

59.5 – 98.0

100

62.9 – 100.0

0.937

<.01

0.752 – 0.992

1 vs. 3+4

WBC

>14.3

75.8

57.7 – 88.9

62.5

24.7 – 91.0

0.644

n.s.

0.479 – 0.787

IL-6

>12.2

75.8

57.7 – 88.9

100

62.9 – 100.0

0.903

<.01

0.770 – 0.973

CRP

>11

69.7

51.3 – 84.4

100

62.9 – 100.0

0.843

<.05

0.695 – 0.937

2 vs. 4

WBC

>18

73.3

44.9 – 92.0

58.8

33.0 – 81.5

0.569

n.s.

0.382 – 0.741

IL-6

>21.7

86.7

59.5 – 98.0

82.4

56.6 – 96.0

0.833

<.02

0.660 – 0.940

CRP

>42

80

51.9 – 95.4

94.1

71.2 – 99.0

0.894

<.005

0.734 – 0.974

2 vs. 3+4

WBC

>12.6

87.9

71.8 – 96.5

41.2

18.5 – 67.0

0.542

n.s.

0.395 – 0.684

IL-6

>21.7

63.6

45.1 – 80.1

82.4

56.6 – 96.0

0.736

<.05

0.592 – 0.851

CRP

>26

66.7

48.1 – 83.1

82.4

56.6 – 96.0

0.731

n.s.

0.587 – 0.846

3 vs. 4

WBC

>18.2

73.3

44.9 – 92.0

61.1

35.3 – 82.9

0.613

n.s.

0.428 – 0.777

IL-6

>23.1

86.7

59.5 – 98.0

66.7

41.0 – 86.6

0.719

n.s.

0.535 – 0.860

CRP

>46

80

51.9 – 95.4

88.9

65.2 – 98.3

0.835

<.05

0.665 – 0.940

1+2 vs. 3+4

WBC

>12.6

87.9

71.8 – 96.5

44

24.4 – 65.1

0.575

n.s.

0.438 – 0.703

IL-6

>12.2

75.8

57.7 – 88.9

76

54.9 – 90.6

0.79

n.s.

0.663 – 0.886

CRP

>26

60.6

42.1 – 77.1

88

68.8 – 97.3

0.767

n.s.

0.637 – 0.868


Sack et al. BMC Surgery 2006 6:15   doi:10.1186/1471-2482-6-15

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