Table 5

Best cut-off values, specifity, sensitivity, and areas under the curve (AUC) with 95 % confidence intervals estimated for CRP, IL-6 and WBC. Significantly best parameters are shown bold with italic p values in comparison to WBC.


Criterion
 Sensitivity
 95% CI
 Specificity
 95% CI
 AUC
 sign.
 95% CI
1 vs. 4
 WBC
 >14.3
 80
 51.9 – 95.4
 62.5
 24.7 – 91.0
 0.667
 n.s.
 0.442 – 0.847

IL-6
 >12.2
 93.3
 68.0 – 98.9
 100
 62.9 – 100.0
 0.992
 <.005
 0.836 – 1.000

CRP
 >11
 86.7
 59.5 – 98.0
 100
 62.9 – 100.0
 0.937
 <.01
 0.752 – 0.992
1 vs. 3+4
 WBC
 >14.3
 75.8
 57.7 – 88.9
 62.5
 24.7 – 91.0
 0.644
 n.s.
 0.479 – 0.787

IL-6
 >12.2
 75.8
 57.7 – 88.9
 100
 62.9 – 100.0
 0.903
 <.01
 0.770 – 0.973

CRP
 >11
 69.7
 51.3 – 84.4
 100
 62.9 – 100.0
 0.843
 <.05
 0.695 – 0.937
2 vs. 4
 WBC
 >18
 73.3
 44.9 – 92.0
 58.8
 33.0 – 81.5
 0.569
 n.s.
 0.382 – 0.741

IL-6
 >21.7
 86.7
 59.5 – 98.0
 82.4
 56.6 – 96.0
 0.833
 <.02
 0.660 – 0.940

CRP
 >42
 80
 51.9 – 95.4
 94.1
 71.2 – 99.0
 0.894
 <.005
 0.734 – 0.974
2 vs. 3+4
 WBC
 >12.6
 87.9
 71.8 – 96.5
 41.2
 18.5 – 67.0
 0.542
 n.s.
 0.395 – 0.684

IL-6
 >21.7
 63.6
 45.1 – 80.1
 82.4
 56.6 – 96.0
 0.736
 <.05
 0.592 – 0.851

CRP
 >26
 66.7
 48.1 – 83.1
 82.4
 56.6 – 96.0
 0.731
 n.s.
 0.587 – 0.846
3 vs. 4
 WBC
 >18.2
 73.3
 44.9 – 92.0
 61.1
 35.3 – 82.9
 0.613
 n.s.
 0.428 – 0.777

IL-6
 >23.1
 86.7
 59.5 – 98.0
 66.7
 41.0 – 86.6
 0.719
 n.s.
 0.535 – 0.860

CRP
 >46
 80
 51.9 – 95.4
 88.9
 65.2 – 98.3
 0.835
 <.05
 0.665 – 0.940
1+2 vs. 3+4
 WBC
 >12.6
 87.9
 71.8 – 96.5
 44
 24.4 – 65.1
 0.575
 n.s.
 0.438 – 0.703

IL-6
 >12.2
 75.8
 57.7 – 88.9
 76
 54.9 – 90.6
 0.79
 n.s.
 0.663 – 0.886

CRP
 >26
 60.6
 42.1 – 77.1
 88
 68.8 – 97.3
 0.767
 n.s.
 0.637 – 0.868

Sack et al. BMC Surgery 2006 6:15   doi:10.1186/1471-2482-6-15