Table 1

Study Selection Criteria.

Population: Patients suspicious to have acute appendicitis

Diagnostic tests:

Prediction rules

Inflammatory markers (C-reactive protein, leucocytes count)

Transabdominal ultrasound

Computer Tomography (CT)

Magnetic Resonance Imaging (MRI)


Diagnostic laparoscopy clinical history and physical examination

Outcome measures: Test accuracy, morbidity and mortality from misdiagnosis

Study design: Diagnostic test studies will be selected. They consist of observational studies (prospective or cross-sectional) of defined non-randomised populations in which the results of the diagnostic test of interest are compared with the results of a reference standard allowing generation of a 2 × 2 table to compute indices of diagnostic accuracy.

Bachmann et al. BMC Surgery 2002 2:2   doi:10.1186/1471-2482-2-2

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