Table 6

SF-36 scores (higher scores indicate less impairment).



Baseline
SAMe
Celecoxib


Variable
N+
Mean
(SD)
Mean
(SD)
Mean
(SD)
Stdif.

Physical Function
53
52.5
(20.8)
62.4*
(22.8)
63.7*
(25.1)
-0.10
Role Physical
53
56.6
(37.4)
66.5*
(33.6)
67.9*
(38.1)
-0.04
Role Emotional
53
86.8
(29.5)
88.7
(24.4)
87.4
(27.1)
0.06
Vitality
53
58.9
(14.4)
60.4
(14.0)
62.9*
(14.5)
-0.23
Mental Health
53
71.8
(11.4)
73.7
(11.3)
74.0
(11.8)
-0.03
Social Function
53
82.3
(20.1)
84.2
(19.8)
86.3
(18.7)
-0.09
Bodily Pain
53
46.8
(14.1)
59.3*
(19.8)
63.1*
(19.6)
-0.16
General Health
53
74.6
(15.2)
75.4
(17.2)
76.6
(16.8)
-0.10
General Physical
53
38.1
(8.2)
42.3*
(9.5)
43.4*
(10.6)
-0.16
General Mental
53
54.6
(7.8)
54.1
(7.4)
54.2
(6.8)
-0.02

Stdif: Standardized difference scores – positive numbers indicate a better response with SAMe. +Sample sizes are less than 57 due to missing data in either Phase 1 or Phase 2. *Difference between baseline and treatment is statistically significant (p < 0.05). No statistically significant differences were observed between SAMe and Celecoxib.

Najm et al. BMC Musculoskeletal Disorders 2004 5:6   doi:10.1186/1471-2474-5-6