Email updates

Keep up to date with the latest news and content from BMC Musculoskeletal Disorders and BioMed Central.

Open Access Research article

Obesity & hypertension are determinants of poor hemodynamic control during total joint arthroplasty: a retrospective review

Benedict U Nwachukwu123, Jamie E Collins27, Emily P Nelson4, Mercedes Concepcion4, Thomas S Thornhill13 and Jeffrey N Katz123456*

Author Affiliations

1 Harvard Medical School, 260 Longwood Avenue, Boston, MA, 02115, USA

2 Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women’s Hospital, 75 Francis St., Boston, MA, 02115, USA

3 Department of Orthopedic Surgery, Brigham and Women’s Hospital, 75 Francis St., Boston, MA, 02115, USA

4 Department of Anesthesia & Critical Care, Brigham and Women’s Hospital, 75 Francis St., Boston, MA, 02115, USA

5 Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, 75 Francis St., Boston, MA, 02115, USA

6 Harvard School of Public Health, 677 Huntington Ave., Boston, MA, 02115, USA

7 Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Talbot Building, Boston, MA, 02118, USA

For all author emails, please log on.

BMC Musculoskeletal Disorders 2013, 14:20  doi:10.1186/1471-2474-14-20

Published: 14 January 2013

Abstract

Background

Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor intra-operative hemodynamic control. The purpose of this study is to identify risk factors for poor hemodynamic control during TJA.

Methods

We performed a retrospective cohort analysis of 118 patients receiving TJA in the Dominican Republic. We collected patient demographic and comorbidity data. We developed an a priori definition for poor hemodynamic control: 1) Mean arterial pressure (MAP) <65% of preoperative MAP or 2) MAP >135% of preoperative MAP. We performed bivariate and multivariate analyses to identify risk factors for poor hemodynamic control during TJA.

Results

Hypertension was relatively common in our study population (76 of 118 patients). Average preoperative mean arterial pressure was 109.0 (corresponding to an average SBP of 149 and DBP of 89). Forty-nine (41.5%) patients had intraoperative blood pressure readings consistent with poor hemodynamic control. Based on multi-variable analysis preoperative hypertension of any type (RR 2.9; 95% CI 1.3-6.3) and an increase in BMI (RR 1.2 per 5 unit increase; 95% CI 1.0-1.5) were significant risk factors for poor hemodynamic control.

Conclusions

Preoperative hypertension and being overweight/obese increase the likelihood of poor blood pressure control during TJA. Hypertensive and/or obese patients warrant further attention and medical optimization prior to TJA. More work is required to elucidate the relationship between these risk factors and overall outcome.

Keywords:
Hip; Knee; Blood pressure; Total joint arthroplasty; Obesity; Hypertension