Table 1

In vitro results of NHAC-kn cultured on HDM_derm and CTR for 7 and 14 days
HDM_derm CTR Two-way ANOVA
7 days 14 days 7 days 14 days
CPII (pg/mg) 79.0 ± 13.5* 145.0 ± 21.2*,° 39.8 ± 13.8 71.0 ± 7.4 F=6.9, p < 0.05
Aggrecan (ng/mg) 490.8 ± 60.0 937.4 ± 76.2***,°°° 517.6 ± 32.8 583.4 ± 20.8 F=66.5, p < 0.0005
TGF-β1 (pg/mg) 2821.7 ± 145.7 2785.6 ± 405.1 3015.7 ± 125.6 2332.3 ± 89.4° F=10.2, p < 0.05
IL-1β (pg/mg) 0.8 ± 0.1 1.0 ± 0.2 0.8 ± 0.0 0.8 ± 0.0 NS
MMP3 (ng/mg) 5.8 ± 3.8** 3.3 ± 1.5 18.6 ± 1.7 5.8 ± 0.2°° F=16.7, p < 0.005

Bonferroni t test (Mean ± SD, n = 8 replicates):

- between HDM_derm and CTR within each experimental time: *, p<0.05; **, p<0.005; ***, p<0.0005.

- between experimental times within each tested membrane: °, p<0.05; °°, p<0.005; °°°, p<0.0005.

Giavaresi et al.

Giavaresi et al. BMC Musculoskeletal Disorders 2013 14:12   doi:10.1186/1471-2474-14-12

Open Data