Figure 2.

Trabecular bone made up by remodeling with reactive bone formation (A) and reduction or disappearance of inter-trabecular spaces (B). Some residual inter-trabecular space shows micro-aggregation of granulocytes, expression of an acute inflammatory process (C), while other inter-trabecular spaces are filled up with bone matrix and fibrosis (D). At the periphery of the bone, in the sub-synovial tissue, fibrosis with chronic flogosis around bone debris may be observed (E).

Manzi et al. BMC Musculoskeletal Disorders 2012 13:50   doi:10.1186/1471-2474-13-50
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