Research article
Second harmonic generation analysis of early Achilles tendinosis in response to in vivo mechanical loading
1 Centre for Hip Health, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, Canada
2 Department of Physical Therapy, University of British Columbia, Vancouver, Canada
3 James Hogg Research Centre-St Paul's Hospital, Vancouver, Canada
BMC Musculoskeletal Disorders 2011, 12:26 doi:10.1186/1471-2474-12-26
Published: 26 January 2011Additional files
Additional file 1:
Figure 1S Glycosaminoglycan distribution in mechanically loaded and sedentary tendon. Alcian blue staining in tendinosis (A) and normal healthy (B) tendon. Tendinosis tendon demonstrates increased sulphated glycosaminoglycan intra- and peri-cellularly, particularly in chains of abnormal-appearing tenocytes. Mast cells also stain blue with this technique in the paratendon regions (not shown). 20× objective lens.
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