Diallyl disulphide regulates the expression of key MMP genes. SW1353 chondrosarcoma cells were treated +/- interleukin-1 (5 ng/ml) and oncostatin M (10 ng/ml), IL-1/OSM, in the absence or presence of increasing doses of diallyl disulphide (DADS) for 6 hrs. Gene expression was measured using qRT-PCR and normalized to the 18S housekeeping gene. Data is shown as mean +/- SEM (n = 3). Statistics are from t-test: *, p < 0.05; **, p < 0.01; ***, p < 0.001.
Williams et al. BMC Musculoskeletal Disorders 2010 11:280 doi:10.1186/1471-2474-11-280