Table 5

Differential gene expression confirmed by real time RT-PCR*

Gene name

Gene ID

Differential Expression* Microarray

Differential Expression* RT-PCR

Description


HLA-DPA1

M27487

5.3

10.5

Major histocompatibility complex, class II, DP alpha


ITGB2

NM_000211

6.6

5.2

Integrin, beta 2


PTGES

AF010316

3.2

3.4

Prostaglandin E synthase


ENPP1

BF057080

1.7

2.1

Ectonucleotide pyrophosphatase/phosphodiesterase 1


ADAMTS5

BI254089

1.7

1.9

ADAM metallopeptidase with thrombospondin type 1 motif, 5


IL26

NM_018402

1.7

4.3

Interleukin 26


TUFT1

NM_020127

2.8

3.9

Matrix metalloproteinase 1


MMP10

NM_002425

-2.7

-3.1

Matrix metalloproteinase 10


*Differential Expression -- the numbers are the ratio of the relative expression level of a specific gene in OA1 meniscal cells to the relative expression level of the specific gene in the control meniscal cells (mixture of RNA prepared from the three normal control meniscal cells).

Sun et al. BMC Musculoskeletal Disorders 2010 11:19   doi:10.1186/1471-2474-11-19

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