|
Predictors of a higher diagnostic yield. Odds ratio (95%CI) in multivariate analysis. |
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| Biopsy (n = 201) |
TBNA (n = 191) |
Brushing (n = 187) |
Aspiration (n = 356) |
All (n = 363) |
|
|
|
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| Endobronchial visibility |
** |
** |
* |
** |
** |
| Non-visible lesion |
1 |
1 |
1 |
1 |
1 |
| Compression/constriction |
2.4 (0.8–7.0) |
1.2 (0.3–4.4) |
0.4 (0.1–1.5) |
0.8 (0.1–4.6) |
2.6 (1.3–5.2) |
| Visible lesion |
10.8 (3.8–30.7) |
5.0 (1.4–17.5) |
3.1 (1.1–8.3) |
6.4 (1.9–20.9) |
17.0 (8.5–34.0) |
| Tumor size |
* |
* |
|||
| <= 2 cm |
1 |
1 |
1 |
1 |
1 |
| 2–3 cm |
7.9 (1.4–45.1) |
0.8 (0.2–4.0) |
1.1 (0.2–7.3) |
2.2 (0.4–12.7) |
2.5 (0.8–7.9) |
| 3–4 cm |
9.4 (1.7–52.2) |
3.1 (0.6–15.3) |
2.8 (0.5–17.0) |
2.1 (0.3–13.6) |
6.7 (2.1–21.8) |
| > 4 cm |
6.7 (1.5–30.6) |
2.0 (0.5–7.6) |
2.0 (0.4–10.9) |
1.0 (0.2–5.4) |
3.8 (1.3–10.7) |
|
Odds ratio adjusted for age, sex, lobe and distance from carina. TBNA = Transbronchial needle aspiration. * Likelihood ratio: p < 0.05. ** Likelihood ratio: p < 0.001. | |||||
Roth et al. BMC Pulmonary Medicine 2008 8:2 doi:10.1186/1471-2466-8-2 |
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