|
Diagnostic yield of different sampling techniques |
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| Biopsy (n = 201) |
TBNA (n = 191) |
Brushing (n = 187) |
SVL (n = 72) |
Aspiration (n = 356) |
All (n = 363) |
|
|
|
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| Overall diagnostic yield |
122/201 (60.7) |
78/191 (40.8) |
43/187 (23.0) |
5/72 (6.9) |
29/356 (8.1) |
161/363 (44.4) |
| Endobronchial visibility |
** |
** |
** |
** |
** |
|
| Non visible lesion |
9/36 (25.0) |
4/21 (19.0) |
13/68 (16.0) |
3/46 (6.5) |
5/130 (3.8) |
22/132 (16.7) |
| Constriction/compression |
22/48 (45.8) |
17/69 (24.6) |
5/49 (10.2) |
1/11 (9.1) |
2/88 (2.3) |
31/90 (34.4) |
| Visible lesion |
91/117 (77.8) |
57/101 (56.4) |
25/57 (43.9) |
1/15 (6.7) |
22/138 (15.9) |
108/141 (76.6) |
| Tumor size |
* |
** |
||||
| <= 2 cm |
3/13 (23.1) |
4/16 (25.0) |
2/19 (10.5) |
0/13 (0.0) |
2/41 (4.9) |
7/41 (17.1) |
| > 2 cm and <= 3 cm |
15/24 (62.5) |
6/18 (25.0) |
4/35 (11.4) |
0/19 (0.0) |
6/59 (10.2) |
20/62 (32.3) |
| > 3 cm and <= 4 cm |
19/35 (54.3) |
12/24 (50.0) |
8/31 (25.8) |
1/13 (7.7) |
4/51 (7.8) |
25/53 (47.2) |
| > 4 cm |
85/129 (65.9) |
56/127 (44.1) |
29/102 (28.4) |
4/27 (14.8) |
17/205 (8.3) |
109/207 (52.7) |
| Distance to carina |
* |
* |
* |
|||
| <= 5 cm |
59/86 (68.6) |
40/93 (43.0) |
23/68 (33.8) |
0/12 (0.0) |
13/142 (9.2) |
78/144 (54.2) |
| > 5 cm |
44/88 (50.0) |
26/74 (35.1) |
17/102 (16.7) |
3/52 (5.8) |
12/165 (6.8) |
62/179 (34.6) |
| Indeterminate |
19/27 (70.4) |
12/24 (50.0) |
3/17 (17.6) |
2/8 (25.0) |
4/37 (10.8) |
21/40 (52.5) |
| Side |
||||||
| Left |
49/80 (61.3) |
26/75 (34.7) |
20/80 (25.0) |
4/27 (14.8) |
14/147 (9.5) |
62/151 (41.1) |
| Right |
68/115 (59.1) |
46/106 (43.4) |
22/103 (21.4) |
1/42 (2.4) |
14/195 (7.2) |
92/198 (46.5) |
| Indeterminate |
5/6 (83.3) |
6/10 (60.0) |
1/4 (25.0) |
0/3 (0.0) |
1/14 (7.1) |
7/14 (50.0) |
| Lobe |
||||||
| Upper lobe without lingula |
47/92 (51.1) |
29/91 (31.9) |
20/92 (21.7) |
3/27 (11.1) |
15/162 (9.3) |
68/164 (41.5) |
| Middle lobe/lingula |
8/13 (61.5) |
6/14 (42.9) |
6/18 (33.3) |
0/9 (0.0) |
0/27 (0.0) |
11/29 (37.9) |
| Lower lobe |
50/74 (67.6) |
29/58 (50.0) |
13/60 (21.7) |
2/30 (6.7) |
11/124 (8.9) |
61/127 (48.0) |
| Mediastinum |
8/11 (72.7) |
7/18 (38.9) |
2/13 (15.4) |
0/5 (0.0) |
0/30 (0.0) |
12/30 (40.0) |
| Indeterminate |
9/11 (81.8) |
7/10 (70) |
2/4 (50.0) |
0/1 (0.0) |
3/13 (23.1) |
9/13 (69.2) |
|
*p < 0.05. **p < 0.001 Data are presented as number of positive samples/all samples (%). Statistical analysis: χ2. TBNA = Transbronchial needle aspiration. SVL = Small volume lavage. | ||||||
Roth et al. BMC Pulmonary Medicine 2008 8:2 doi:10.1186/1471-2466-8-2 |
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