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Open Access Highly Accessed Research article

Clinical presentation and predictors of outcome in patients with severe acute exacerbation of chronic obstructive pulmonary disease requiring admission to intensive care unit

Alladi Mohan*, Raya Premanand, Lebaka Narayana Reddy, Mangu H Rao, Surendra K Sharma, Ranjit Kamity and Srinivas Bollineni

BMC Pulmonary Medicine 2006, 6:27  doi:10.1186/1471-2466-6-27

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Statistical Error

Surya Bhatt   (2007-01-10 13:36)  St Luke email

This paper is, in general, well written. However I would like to point out some glaring discrepancies in Table 5. When the 95% confidence interval crosses one as for hypercapnia, it would not be significant. Also, to say hypercapnia and presence of co-morbidity significantly predicted death would be wrong as the odds ratio is less than one, suggesting exactly the opposite! Co-morbid illnesses have not been adequately defined in methods and would have been better quatified by using standard indices like the Charlson's Index.Whether the end point was in-hospital mortality is again not clear.

Competing interests

I have no competing interests

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