Table 1 |
||
|
Variables to be collected in the cross-sectional and nested case-control studies |
||
|
Cross-sectional |
Case-control |
|
|
|
||
|
Allergy questions |
||
|
Core asthma symptom questions (ISAAC phase II) |
X |
X |
|
Core rhinitis symptom questions (ISAAC phase II) |
X |
X |
|
Core eczema symptom questions (ISAAC phase II) |
X |
X |
|
Supplementary asthma questions (ISAAC phase II) |
X |
|
|
Asthma management questions (ISAAC phase II) |
X |
|
|
Rhinitis management questions (ISAAC phase II) |
X |
|
|
Eczema management questions (ISAAC phase II) |
X |
|
|
Knowledge attitude practice questions (KAP) |
X |
|
|
Demographic and socio-economic |
||
|
Sex |
X |
X |
|
Age |
X |
X |
|
Race |
X |
X |
|
On socio-economic level: |
||
|
parental schooling |
X |
|
|
parental occupation |
X |
X |
|
domestic goods |
X |
X |
|
monthly income |
X |
X |
|
Environmental factors |
||
|
Sanitation and water supply |
X |
X |
|
Does the house have electricity? |
X |
X |
|
Pets |
||
|
Has the child ever had a cat or dog living in the house? |
X |
|
|
Does the child have a cat or dog living in the house currently? |
X |
X |
|
Presence of animals outside household |
X |
X |
|
Indoor smoking |
X |
X |
|
Exposure to a farming environment |
X |
X |
|
Housing (e.g. construction, number of rooms) |
X |
X |
|
Presence of allergens in dust (mites and cockroach) |
X |
|
|
Presence of endotoxin in the house |
X |
|
|
Cooking materials |
X |
X |
|
Maternal and family related factors |
||
|
Maternal smoking during pregnancy |
X |
|
|
Asthma and other allergic diseases in the family |
X |
|
|
Breast-feeding duration |
X |
|
|
Vaccination (BCG, DTP, measles) |
X |
|
|
Whether attended day care (and for what period) |
X |
|
|
Number of people who live in each household |
X |
X |
|
Number of siblings or children in the household |
X |
X |
|
Birth order |
X |
X |
|
Diet |
||
|
Food frequency questionnaire |
X |
X |
|
Consumption of unpasteurized milk |
X |
|
|
Migration |
||
|
Place of birth of child |
X |
|
|
Place of birth of father |
X |
|
|
Place of birth of mother |
X |
|
|
Was the father brought up in an urban or rural area? |
X |
|
|
Was the mother brought up in an urban or rural area? |
X |
|
|
Period of time and places living outside place of birth during first 5 years of life |
X |
|
|
Details of relatives living in the city of Esmeraldas |
X |
|
|
Exercise/sedentarism |
||
|
Number of hours of television watched daily |
X |
X |
|
Frequency of vigorous exercise |
X |
X |
|
Nutritional assessment |
||
|
Hemoglobin |
X |
X |
|
Height |
X |
X |
|
Weight |
X |
X |
|
Mid-upper arm circumference |
X |
|
|
Triceps skin fold thickness |
X |
|
|
Specific Infections |
||
|
Intestinal helminth and protozoal infections (stool examinations) |
X |
X |
|
A. lumbricoides IgE |
X |
|
|
IgG for Toxoplasma. Gondii, Helicobacter pylori and viral infections |
X |
|
|
Exercise test for exercise-induced bronchospasm |
X |
|
|
Atopy |
||
|
Skin prick test |
X |
X |
|
Total and specific IgE titres to house dust mite and American cockroach |
X |
|
|
Immunoregulatory cytokines |
||
|
IL-10, IL-13, IFN-γ |
X |
|
|
|
||
|
Cooper et al. BMC Pulmonary Medicine 2006 6:24 doi:10.1186/1471-2466-6-24 |
||