Table 1

Effect of increased peak inspiratory pressure on ventilation, FRC and ventilatory inhomogeneity indices in 15 ventilated piglets (Presented are groups means ± SD and the mean individual changes with 95%CI compared to the baseline)


Baseline
Increased peak inspiratory pressure
Mean individual difference in % with 95%CI
P value

VT (mL)
15.4 ± 9.5
21.9 ± 14.7
38.9 (20.4 to 57.45)
p = 0.003
FRC (mL)
31.6 ± 14.7
35.0 ± 15.9
11.1 (4.5 to 17.8)
p = 0.006
VT/FRC
0.48 ± 0.17
0.59 ± 0.20
25.0 (10.7 to 39.4)
p = 0.003
VD/VT
0.49 ± 0.15
0.43 ± 0.13
-10.2 (-21.0 to 0.5)
p = 0.006
LCI
9.17 ± 0.75
8.55 ± 0.74
-6.4 (-11.8 to -1.0)
p = 0.019
M1/M0
2.03 ± 0.16
1.84 ± 0.16
-9.4 (-14.0 to -4.9)
p = 0.006
M2M0
8.41 ± 1.60
7.22 ± 4.80
-12.1 (-23.1 to -1.4)
p = 0.017
AMDN1
1.034 ± 0.30
1.028 ± 0.19
-0.6 (-9.1 to 7.9)
p = 0.886
AMDN2
2.88 ± 1.56
3.01 ± 1.06
4.5 (-9.9 to 18.1)
p = 0.515

Schmalisch et al. BMC Pulmonary Medicine 2006 6:20   doi:10.1186/1471-2466-6-20