Table 6

Lung function measures according to exposure from oil tank explosion in men and women
Control Exposed Difference between exposed <6 km and control Difference between exposed 3-6km and control Difference between exposed <3 km and control
Men n = 91 n = 99
AM (SD)a AM (SD)a AM difference (95% CI)b AM difference (95% CI)b AM difference (95% CI)b
FEV1 (mL) 3860 (827) 3746 (843) - 137 (−307, 32) −87 (−336, 161) −194 (−406, 18)
FEV1% predicted 90.7 (13.8) 88.5 (14.9) −1.6 (−5.7, 2.5) −0.6 (−6.6, 5.4) −2.7 (−8.8, 3.5)
FVC (mL) 5125 (843) 4902 (880) −242 (−435, -50) −212 (−497, 73) −275 (−569, 18)
FVC% predicted 99.5 (11.8) 96.1 (13.0) −3.7 (−7.4, 0.0) −2.4 (−7.9, 3) −5.1 (−10.6, 0.5)
FEV1/FVC ratio 0.75 (0,08) 0.76 (0,08) 0.01 (−0.01, 0.03) 0.02 (−0.01, 0.05) 0.00 (−0.02, 0.03)
n (%) n (%)
Airway obstruction c before salbutamol 5 (6) 14 (14)
Airway obstruction c after salbutamol 4 (4) 9 (9)
Women n = 71 n = 94
AM (SD)a AM (SD)a AM difference (95% CI)b AM difference (95% CI)b AM difference (95% CI)b
FEV1 (mL) 2896 (543) 2775 (700) −99 (−235, 37) −206 (−402, -10) 5 (−190, 199)
FEV1% predicted 95.7 (12.8) 90.6 (15,4) −3.5 (−8.1, 1.1) −7.2 (−13.9, -0.5) 0.0 (−6.6, 6.5)
FVC (mL) 3667 (625) 3567 (807) −92(−250, 87) −252 (−478, -27) 66 (−158, 289)
FVC% predicted 99.8 (12,2) 96.6 (13.8)) −1.6 (−6.4, 3.2) −6.5 (−12.6, -0.4) 1.0 (−5.0, 7.0)
FEV1/FVC ratio 0.80 (0.06) 0.77 (0.09) −0.01 (−0.3, 0.01) −0.01 (−4.2, 2.3) −1.4 (−4.6, 1.9)
n (%) n (%)
Airway obstructionc before salbutamol 3 (4) 7 (7)
Airway obstructionc after salbutamol 1 (2) 6 (6)

Exposed status was defined as living <6 km (average 3.7 km) from the explosion site; control status as living >20 km (average 28 km) from the explosion site. Increasing intensity of exposure was defined by dividing the exposed in those living 3–6 km (average 4.7 km) and <3 km (average 2.6 km) from the explosion site

a Arithmetic mean (Standard deviation). b Arithmetic mean difference (95% confidence interval) between exposure groups and control group from linear regression models adjusted for smoking, occupational exposure, atopy (defined by Phadiatop® ), infection in the preceding month, height and age (models for FEV1% predicted and FVC% predicted not adjusted for height and age). c Airway obstruction defined as FEV1/FVC < 0.70 and FEV1% predicted <0.8.

Granslo et al.

Granslo et al. BMC Pulmonary Medicine 2012 12:76   doi:10.1186/1471-2466-12-76

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