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Open Access Research article

Factors associated with improvement in disability-adjusted life years in patients with HIV/AIDS

Clara Bermudez-Tamayo1*, Jose Jesus Martin Martin2, Isabel Ruiz-Pérez3 and Antonio Olry de Labry Lima3

Author Affiliations

1 Andalusian School of Public Health, Granada, Spain

2 Department of Applied Economics, University of Granada, Granada, Spain

3 Andalusian School of Public Health, CIBER de Epidemiología y Salud Pública (CIBERESP), Granada, Spain

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BMC Public Health 2008, 8:362  doi:10.1186/1471-2458-8-362

Published: 21 October 2008

Abstract

Background

The epidemic of HIV/AIDS and treatments that have emerged to alleviate, have brought about a shift in the burden of disease from death to quality of life/disability. The aim was to determine which factors are associated with improvements in the level of health of male and female patients with HIV/AIDS in Andalusia, in terms of disability-adjusted life years.

Methods

Descriptive study based on a sample group of 8800 people on the Andalusian AIDS register between 1983 and 2004. Dependent variables: Life lost due to premature mortality (YLL), years lost due to disability (YLD) and disability-adjusted life years (DALY). Independent variables: vital state, sex, age at the time of diagnosis, age at the time of death, transmission category, province of residence, AIDS-indicator disease and the period of diagnosis. A bivariate analysis was carried out to find out if the health level variables changed in accordance with the independent variables. Using the independent variables which had a statistically significant link with the level of health variables, a multivariate linear regression model, disaggregated by gender, was constructed.

Results

Amongst the women, we found a model which explained the level of health of 64.9%: a link was found between a higher level of health (lower DALYs) and not intravenous drug use, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis. Amongst the men, we found a model which explained the level of health of 64.4%: a link was found between a higher level of health (lower DALYs) and intravenous drug use, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis.

Conclusion

A higher level of health (lower DALY) amongst both men and women was found to be linked to not be intravenous drug user, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis.