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Cocaine- and opiate-related fatal overdose in New York City, 1990–2000

Kyle T Bernstein1 email, Angela Bucciarelli2 email, Tinka Markham Piper2 email, Charles Gross3 email, Ken Tardiff3 email and Sandro Galea4,5 email

1Department of Emergency Medicine, School of Medicine, New York University. 462 First Ave, 3rd Floor, Room A345, NY, NY 10003. USA

2Center for Urban Epidemiologic Studies, New York Academy of Medicine, 1216 Fifth Ave, NY, NY 10029, USA

3Department of Psychiatry, Weill Medical College, Cornell University, 525 E. 68th St, NY, NY 10021 USA

4Department of Epidemiology, School of Public Health, University of Michigan. 1214 South University, Ann Arbor, Michigan, 48104-2548, USA

5Department of Epidemiology, Columbia University Mailman School of Public Health. 722 168th St, New York, New York 10032, USA

author email corresponding author email

BMC Public Health 2007, 7:31doi:10.1186/1471-2458-7-31

Published: 9 March 2007

Abstract

Background

In New York City (NYC), the annual mortality rate is higher for accidental drug overdoses than for homicides; cocaine and opiates are the drugs most frequently associated with drug overdose deaths. We assessed trends and correlates of cocaine- and opiate-related overdose deaths in NYC during 1990–2000.

Methods

Data were collected from the NYC Office of the Chief Medical Examiner (OCME) on all fatal drug overdoses involving cocaine and/or opiates that occurred between 1990–2000 (n = 8,774) and classified into three mutually exclusive groups (cocaine only; opiates-only; cocaine and opiates). Risk factors for accidental overdose were examined in the three groups and compared using multinomial logistic regression.

Results

Overall, among decedents ages 15–64, 2,392 (27.3%) were attributed to cocaine only and 2,825 (32.2%) were attributed to opiates-only. During the interval studied, the percentage of drug overdose deaths attributed to cocaine only fell from 29.2% to 23.6% while the percentage of overdose deaths attributed to opiates-only rose from 30.6% to 40.1%. Compared to New Yorkers who fatally overdosed from opiates-only, fatal overdose attributed to cocaine-only was associated with being male (OR = 0.71, 95% CI 0.62–0.82), Black (OR = 4.73, 95% CI 4.08–5.49) or Hispanic (OR = 1.51, 95% CI 1.29–1.76), an overdose outside of a residence or building (OR = 1.34, 95% CI 1.06–1.68), having alcohol detected at autopsy (OR = 0.50, 95% CI 0.44–0.56) and older age (55–64) (OR = 2.53 95% CI 1.70–3.75)).

Conclusion

As interventions to prevent fatal overdose become more targeted and drug specific, understanding the different populations at risk for different drug-related overdoses will become more critical.


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