Table 5 |
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Sensitivity analysis for projected savings over 20 years with DOTS expansion in Haiti |
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SAVINGS in $US MILLIONS WITH DOTS EXPANSION * |
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|
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PERSPECTIVE |
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|
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|
PARAMETER VARIED |
CHANGE |
NEW VALUE |
SOCIETAL |
GOVERNMENT |
|
|
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|
Base Case (from Table 4) |
Base |
Base |
($131) |
($4) |
|
Initial DOTS investment |
Double |
$8.4 million total |
($126) |
($0) |
|
Annual DOTS maintenance |
Double |
$722,000 per year |
($128) |
($1) |
|
Annual DOTS maintenance + cost of TB drugs |
Double both |
$847,900 per year |
($128) |
($1) |
|
Foreign Donor Pays: Initial + annual + TB drugs |
Eliminate all three |
$8.44 million + $847,000 per year |
($138) |
($11) |
|
Change average duration of hospitalization |
Decrease with DOTS, increase with Non-DOTS |
3 days – DOTS 60 days non-DOTS |
($165) |
($29) |
|
Single (SDR) and Multi (MDR) Drug resistance |
Double prevalence of drug resistance |
SDR : 40% MDR : 0.6% |
($131) |
($4) |
|
Impact of DOTS expansion on TB incidence in subsequent years |
None 1/3 of base 2/3 of base |
0% annual decline 2% annual decline 4% annual decline |
($61) ($88) ($111) |
$ 14 * $ 7* $ 1* |
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Notes: * A number in parentheses indicates net societal or government savings, while a number not in parentheses indicates a net increased cost with DOTS expansion,. |
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Jacquet et al. BMC Public Health 2006 6:209 doi:10.1186/1471-2458-6-209 |
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