Table 7 |
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|
Adjusted odds ratios for various factors that might affect treatment outcomes among registered tuberculosis patients |
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|
Treatment success (all TB) |
Default (all TB) |
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|
|
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|
Characteristic |
Percent1 |
Adjusted OR* (95% CI) |
p-value |
Percent1 |
Adjusted OR* (95% CI) |
p-value |
|
|
||||||
|
Sex |
||||||
|
Male |
45.5 |
1.00 |
37.5 |
1.00 |
||
|
Female |
49.4 |
1.15(1.08–1.23) |
<0.001 |
34.0 |
0.88(0.82–0.94) |
<0.001 |
|
Age group (years) |
||||||
|
0–14 |
42.6 |
0.83 (0.75–0.92) |
<0.001 |
41.2 |
1.17 (1.06–1.30) |
0.002 |
|
15–24 (reference group) |
51.1 |
1.00 |
33.4 |
1.00 |
||
|
25–34 |
47.5 |
0.84(0.77–0.91) |
<0.001 |
34.4 |
1.07 (0.98–1.17) |
0.14 |
|
35–44 |
45.7 |
0.76 (0.68–0.84) |
<0.001 |
36.1 |
1.14 (1.03–1.28) |
0.02 |
|
45–54 |
44.9 |
0.69 (0.60–0.79) |
<0.001 |
37.7 |
1.26 (1.09–1.46) |
0.002 |
|
55–64 |
51.4 |
1.04 (0.84–1.29) |
0.71 |
35.4 |
1.04 (0.81–1.27) |
0.90 |
|
≥ 65 |
37.4 |
0.67 (0.48–0.93) |
0.02 |
43.7 |
1.27 (0.92–1.726 |
0.15 |
|
Patient category |
||||||
|
New |
47.0 |
1.00 |
35.9 |
1.00 |
||
|
Transferred-in |
59.5 |
1.09 (0.89–1.36) |
0.40 |
35.7 |
1.19 (0.95–1.48) |
0.13 |
|
Return after default |
33.9 |
0.68 (0.51–0.92) |
0.01 |
52.9 |
1.57 (1.19–2.07) |
0.002 |
|
Treatment failure |
54.3 |
1.30 (0.91–1.86) |
0.15 |
23.6 |
0.72 (0.48–1.09) |
0.12 |
|
Relapse |
62.9 |
1.51(1.01–2.26) |
0.05 |
16.9 |
0.50 (0.30–0.82) |
0.006 |
|
TB type |
||||||
|
Pulmonary positive |
55.3 |
1.00 |
28.7 |
1.00 |
||
|
Pulmonary negative |
37.5 |
0.55 (0.50–0.60) |
<0.001 |
43.7 |
2.06 (1.87–2.26) |
<0.001 |
|
Extra-pulmonary |
42.4 |
0.51 (0.47–0.55) |
<0.001 |
41.1 |
1.94 (1.78–2.11) |
<0.001 |
|
Treatment regimen |
||||||
|
Short course chemotherapy |
55.5 |
1.00 |
27.7 |
1.00 |
||
|
Long course chemotherapy |
45.0 |
0.68 (0.62–0.75) |
<0.001 |
40.9 |
1.46 (1.33–1.61) |
<0.001 |
|
Treatment Centre** |
||||||
|
Hossana Hospital |
27.0 |
1.00 |
40.0 |
1.00 |
||
|
Lemmo district HF |
60.4 |
5.14 (4.62–5.72) |
<0.001 |
20.6 |
0.28 (0.25–0.31) |
<0.001 |
|
Shashogo district HF |
50.8 |
2.81 (2.41–3.28) |
<0.001 |
44.1 |
1.18 (1.01–1.37) |
0.04 |
|
Misha district HF |
60.3 |
4.78 (4.23–5.39) |
<0.001 |
33.0 |
0.58 (0.51–0.65) |
<0.001 |
|
Gibe district HF |
60.7 |
4.78 (4.20–5.45) |
<0.001 |
26.2 |
0.51 (0.45–0.59) |
<0.001 |
|
Soro district HF |
50.5 |
2.70 (2.39–3.06) |
<0.001 |
42.5 |
1.11 (0.98–1.26) |
0.09 |
|
Duna district HF |
30.2 |
0.77 (0.55–1.08) |
0.12 |
67.3 |
5.18 (3.71–7.24) |
<0.001 |
|
Badewacho district HF |
41.1 |
1.64 (1.44–1.86) |
<0.001 |
54.4 |
2.11 (1.86–2.40) |
<0.001 |
|
Year of treatment |
||||||
|
1994 |
38.4 |
1.00 |
42.7 |
1.00 |
||
|
1995 |
40.6 |
1.18 (0.99–1.39) |
0.06 |
39.9 |
1.17 (1.00–1.37) |
0.05 |
|
1996 |
48.7 |
1.29 (1.10–1.51) |
0.002 |
33.3 |
0.83 (0.71–0.97) |
0.02 |
|
1997 |
38.9 |
0.72 (0.61–0.85) |
<0.001 |
39.5 |
1.08 (0.93–1.27) |
0.32 |
|
1998 |
41.9 |
0.74 (0.63–0.87) |
<0.001 |
43.8 |
1.20 (1.03–1.40) |
0.02 |
|
1999 |
56.7 |
1.37 (1.16–1.62) |
<0.001 |
30.0 |
0.59 (0.5–0.70) |
<0.001 |
|
2000 |
59.8 |
1.41 (1.18–1.69) |
<0.001 |
25.8 |
0.54 (0.45–0.65) |
<0.001 |
|
|
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|
OR = odds ratio; CI = confidence intervals; HF = Health facilities * All the variables in the table are included in the model. ** All treatment centres in a district grouped together as a unit. 1 Percentage out of total registered for treatment. Patients with missing outcome record were assumed to have defaulted and analysed as defaulters. |
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|
Shargie and Lindtjørn BMC Public Health 2005 5:62 doi:10.1186/1471-2458-5-62 |
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