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Open Access Research article

Incidence and risk factors for AIDS-related mortality in HIV patients in China: a cross-sectional study

Hui Zheng1, Lu Wang2, Peng Huang1, Jessie Norris2, Qing Wang1, Wei Guo2, Zhihang Peng1*, Rongbin Yu1 and Ning Wang2*

Author Affiliations

1 Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China

2 National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

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BMC Public Health 2014, 14:831  doi:10.1186/1471-2458-14-831

Published: 11 August 2014

Abstract

Background

To estimate the incidence and risk factors for mortality in HIV-1-infected patients in China.

Methods

Information on AIDS-related deaths was collected from the Chinese Center for Disease Control and Prevention’s Disease Surveillance Information Reporting System and AIDS Prevention and Control Information System.

Results

A total of 379,348 HIV cases were recorded in the databases from 2006. Among those, 138,288 patients were reported as having developed AIDS and 72,616 (19%) died of AIDS after data was extracted from the databases in January 2011. Mortality was higher among those patients aged 50 years old or older (AOR: 3.41, CI: 1.47-7.91) who had been infected by intravenous drug use (AOR: 1.65, CI: 1.28-2.14) or blood transfusion/donation (AOR: 2.18: 1.18-3.99). Compared to patients who had not initiated highly active antiretroviral therapy (HAART), those who had initiated HAART were more likely to have a long interval of time between infection confirmation and AIDS-related death.

Conclusions

The effective reduction of AIDS mortality could be improved through timely treatment.

Keywords:
HIV/AIDS; Highly active antiretroviral treatment; Mortality; China