Table 4

Risk factors for increased total cholesterol (TC) level in 1582 HIV subjects (normal = 725, increased TC = 857) on ARV medication
Characteristics Normal Increased TC aOR 95.0 C.I. for OR p-value
Mean ± S.D. Mean ± S.D. Lower Upper
N (%) N (%)
Age (year)
Mean ± SD 43.87 ± 10.09 44.88 ± 9.65 1.010 1.000 1.021 0.043
Gender
Male 608 (83.9) 665 (77.6) 1.00
Female 117 (16.1) 192 (22.4) 1.500 1.163 1.936 0.002
Hypertension
No 565 (81.6) 621 (75.5) 1.00
Yes 127 (18.4) 201 (24.5) 1.440 1.122 1.848 0.004
ARV medication
Without PI 649 (91.3) 731 (87.0) 1.00
With PI 62 (8.7) 109 (13.0) 1.561 1.123 2.169 0.008
Viral load (copies/mL)
≥20 115 (15.9) 98 (11.4) 1.00
<20 610 (84.1) 759 (88.6) 1.460 1.093 1.951 0.010
LDL (mmol/l) 2.37 ± 0.72 3.57 ± 0.97 6.977 5.705 8.534 0.001
<3.36 705 (97.4) 317 (37.2) 1.00
≥3.36 19 (2.6) 536 (62.8) 20.150 12.928 31.406 0.001
TG (mmol/l) 2.03 ± 1.29 2.73 ± 2.09 1.312 1.220 1.412 0.001
<5.17 363 (50.1) 283 (33.1) 1.00
≥5.17 361 (49.9) 571 (66.9) 2.029 1.655 2.487 0.001
HDL (mmol/l) 1.31 ± 0.70 1.32 ± 0.40 1.034 0.866 1.234 0.714
Low 256 (35.6) 196 (22.9) 1.00
Normal§ 466 (64.4) 661 (77.1) 1.867 1.498 2.327 0.001
Hepatitis
No 612 (84.4) 781 (91.1) 1.00
Yes 113 (15.6) 76 (8.9) 0.527 0.387 0.718 0.001

§ ≥1.03 (Male) and ≥1.30 (Female). ARV: Antiretroviral. Adjusted for age, gender, ethnicity, hypertension, diabetes mellitus, CD4, HIV RNA Load, TG, LDL, HDL, FPG, alcohol consumption, smoking, liver disease, medication with agents including ARV (PI), b-blocker, anti-hyperglycemic. aOR Adjusted odds ratio.

Hejazi et al.

Hejazi et al. BMC Public Health 2013 13:758   doi:10.1186/1471-2458-13-758

Open Data