Table 2

Risk factors for increased triglyceride (TG) in 1579 HIV subjects (normal = 646, increased TG = 933) on ARV medication
Characteristics Normal Increased triglyceride aOR 95.0 C.I. for OR p-value
Mean ± S.D. Mean ± S.D. Lower Upper
N (%) N (%)
Age (per year) 43.41 ± 10.51 45.14 ± 9.36 1.018 1.008 1.029 0.001
Gender
Male 484 (74.9) 788 ( 84.5) 1.00
Female 162 (25.1) 145 ( 15.5) 0.550 0.428 0.707 0.001
Ethnicity
Indian 62 (9.7) 96 (10.3) 1.00
Malay 190 (29.8) 199 (21.4) 0.676 0.464 0.985 0.042
Chinese 386 (60.5) 635 (68.3) 1.062 0.754 1.498 0.730
Hypertension
No 515 (82.4) 670 (75.5) 1.00
Yes 110 (17.6) 217 (24.5) 1.516 1.173 1.960 0.010
ARV medication
Without PI 591 (93.6) 786 (85.9) 1.00
With PI 42 (6.4) 129 (14.1) 2.309 1.605 3.324 0.001
b-Blocker
Not taking 620 (96.0) 872 (93.5)
Taking 26 (4.0) 61 (6.5) 1.668 1.042 2.670 0.033
Anti-hyperglycaemic agent
Taking 45 (7.0) 103 (11.0)
Not taking 601 (93.0) 830 (89.0) 0.603 0.419 0.870 0.006
Diabetes mellitus
No 565 (77.5) 765 (82.0) 1.00
Yes 81 (12.5) 186 (18.0) 1.532 1.150 2.040 0.004
TC (mmol/l) 5.05 ± 1.00 5.43 ± 1.40 1.281 1.179 1.392 0.001
<5.17 363 (56.2) 361 (38.7) 1.00
≥5.17 283 (59.1) 571 (40.9) 2.029 1.655 2.487 0.001
HDL (mmol/l) 1.43 ± 0.44 1.24 ± 0.61 0.485 0.384 0.612 0.001
Normal§ 551 (85.3) 576 (61.8) 1.00
Low 95 (14.7) 356 (38.2) 3.585 2.779 4.625 0.001
FPG (mmol/l) 5.52 ± 1.37 5.91 ± 1.95 1.166 1.084 1.253 0.001
Normal 432 (68.7) 519 (57.2) 1.00
High 197 (31.3) 389 (42.8) 1.644 1.327 2.035 0.001
Alcohol
Not Taking 635 (98.3) 892 (95.6) 1.00
Taking 11 (1.7) 41 (4.4) 2.653 1.353 5.202 0.004
Hepatitis
No 546 (84.5) 844 (90.5)
Yes 100 (15.5) 89 (9.5) 0.576 0.424 0.781 0.001

§ ≥ 1.03 ( Male) and ≥ 1.30 (Female). ARV: Antiretroviral. Adjusted for age, gender, ethnicity, hypertension, diabetes mellitus, CD4, HIV RNA Load, TC, LDL, HDL, FPG, alcohol consumption, smoking, liver disease, medication with agents including ARV (PI), b-blocker, anti-hyperglycemic. aOR Adjusted odds ratio.

Hejazi et al.

Hejazi et al. BMC Public Health 2013 13:758   doi:10.1186/1471-2458-13-758

Open Data