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Open Access Research article

Effectiveness of a prevention of mother-to-child HIV transmission program in Guangdong province from 2007 to 2010

Bing Li12, Qingguo Zhao2, Xiaozhuang Zhang2, Li Wu2, Tingting Chen2, Zhijiang Liang2, Longchang Xu2 and Shouyi Yu1*

Author affiliations

1 Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou North Road 1838, Guangzhou 510515, China

2 Guangdong Women and Children Hospital, Xingnan Road 521, Guangzhou 511400, China

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Citation and License

BMC Public Health 2013, 13:591  doi:10.1186/1471-2458-13-591

Published: 18 June 2013

Abstract

Background

To achieve the goal of United Nations of elimination of new HIV infections, a program of prevention of mother-to-child transmission (PMTCT) was launched in Guangdong province. The objective of this study is to evaluate the effectiveness of the PMTCT program.

Methods

The retrospective cross-section analysis was conducted using the data of case reported cards of HIV positive mothers and their infants from 2007 to 2010 in Guangdong province, and 108 pairs of eligible subjects were obtained. We described the data and compared the rates of MTCT by various PMTCT interventions respectively.

Results

The overall rate of HIV MTCT was 13.89% (15) among 108 pairs of HIV positive mothers and their infants; 60.19% (65) of the mothers ever received ARVs, 80.56% (87) of infants born to HIV positive mothers ever received ARVs, but 16.67% (18) of the mothers and infants neither received ARVs. Among all the mothers and infants, who both received ARVs, received triple ARVs, mother received ARVs during pregnancy, and both received ARVs and formula feeding showed the lower rates of HIV MTCT, and the rates were 8.06%, 2.50%, 5.77%, and 6.67% respectively. In infants born to HIV positive mother, who received mixed feeding had a higher HIV MTCT up to 60.00%. Delivery mode might not relative to HIV MTCT.

Conclusions

The interventions of PMTCT program in Guangdong could effectively reduce the rate of HIV MTCT, but the effectiveness of the PMTCT program were heavily cut down by the lower availability of the PMTCT interventions.

Keywords:
HIV/AIDS; Mother to children transmission (MTCT); Anti-retroviral (ARV); Effectiveness of PMTCT