Table 1

In utero and first year of life exposures to air pollutants sources and their temporal sequence with asthma phenotypes in children of the EDEN mother-child cohort study
Period of life/Air pollutant and related sources Corresponding questions Temporal sequence of asthma phenotypes in relation to exposure
Exposure assessed in the first of life (at the period of the outcome) In utero exposure (preceding the outcome)
In utero life
  Prenatal maternal smoking 1. Did you smoke during the first trimester of pregnancy? No Yes
2. Did you smoke during the second trimester of pregnancy?
3. Did you smoke during the third trimester of pregnancy?
  Traffic-related air pollution 1. Does your house located near a bus stop or a passageway of trucks? No Yes
2. Does the cars often or continuously pass by your house?
First year of life
  Heavy parental smoking in the last 12 months 1. Did you smoke at present? Yes No
2. An answer of “more than 20” to the question “How many cigarettes do you smoke every day?”
  Traffic-related air pollution in the last 12 months 1. Do you live less than 200 meters away from a road with heavy traffic? Yes No
2. Notably, Google Earth was used to check the validity of maternal reporting by taking into account a 200 m circular buffer and more than 10,000 vehicles per day (traffic volumes were provided by local authorities) using the home address as reference..
  Dampness in the last 12 months Are there any problems of dampness, moisture or condensation that have often, or permanently, existed in the house since the birth of the child? Yes No
  Visible moulds in the past 12 months Are there any visible moulds that have often, or permanently, existed in the house of the child since the birth of the child? Yes No
  Bleaching agents in the past 12 months Do you often clean with or use the bleaching agents in the presence of the child? Yes No
  House dust mites in the past 12 months Has your child frequently been in contact with carpets, or glazing, or curtains? Yes No
  Contact with cats in the past 12 months 1. Was there a new cat in your house and (or) did you let the cat enter the sleeping room of the child? Yes No
2. Did your child contact with cats outside your house at least once per week?
  Contact with dogs in the past 12 months 1. Was there a new dog in your house and (or) did you let the dog enter the sleeping room of the child? Yes No
2. Did your child contact with dogs outside your house at least once per week?
  Type of domestic heating in the past 12 months Which is your main type of heating in the house: gas, petroleum, wood or others? Yes No

Zhou et al.

Zhou et al. BMC Public Health 2013 13:506   doi:10.1186/1471-2458-13-506

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