The Saving and Empowering Young Lives in Europe (SEYLE) Randomized Controlled Trial (RCT): methodological issues and participant characteristics
1 National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden
2 WHO Collaborating Center for Research, Methods Development and Training in Suicide Prevention, Stockholm, Sweden
3 Department of Child and Adolescent Psychiatry, Columbia University-New York State Psychiatric Institute, New York, USA
4 Department of Health Sciences, University of Molise, Campobasso, Italy
5 Feinberg Child Study Centre, Schneider Children’s Medical Centre, Tel Aviv University, Tel Aviv, Israel
6 Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary
7 Institute of Psychology, Eötvös Loránd University, Budapest, Hungary
8 Department of Psychiatry, University of Oviedo, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Oviedo, Spain
9 Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Heidelberg, Germany
10 Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany
11 National Suicide Research Foundation, Cork, Ireland
12 Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
13 Inserm CIC-EC, Nancy University Hospital, Nancy, France
14 Research Division for Mental Health, University for Medical Information Technology (UMIT), Hall in Tirol, Austria
15 Department of Psychiatry, Centre Hospitalo-Universitaire de Nancy, Université ed Lorraine, Nancy, France
16 Semmelweis University, School of Ph.D. Studies, Budapest, Hungary
17 Slovene Center for Suicide Research, UP IAM, University of Primorska, Koper, Slovenia
18 Clinical Ethics Support & Accompanying Research, University Hospital Basel, Basel, Switzerland
19 Psychiatric Clinics of the University Basel, IBMB, University of Basel, Basel, Switzerland
20 Estonian-Swedish Mental Health & Suicidology Institute, Ctr. Behav. & Hlth. Sci, Tallinn University, Tallinn, Estonia
21 Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA
BMC Public Health 2013, 13:479 doi:10.1186/1471-2458-13-479Published: 16 May 2013
Mental health problems and risk behaviours among young people are of great public health concern. Consequently, within the VII Framework Programme, the European Commission funded the Saving and Empowering Young Lives in Europe (SEYLE) project. This Randomized Controlled Trial (RCT) was conducted in eleven European countries, with Sweden as the coordinating centre, and was designed to identify an effective way to promote mental health and reduce suicidality and risk taking behaviours among adolescents.
To describe the methodological and field procedures in the SEYLE RCT among adolescents, as well as to present the main characteristics of the recruited sample.
Analyses were conducted to determine: 1) representativeness of study sites compared to respective national data; 2) response rate of schools and pupils, drop-out rates from baseline to 3 and 12 month follow-up, 3) comparability of samples among the four Intervention Arms; 4) properties of the standard scales employed: Beck Depression Inventory, Second Edition (BDI-II), Zung Self-Rating Anxiety Scale (Z-SAS), Strengths and Difficulties Questionnaire (SDQ), World Health Organization Well-Being Scale (WHO-5).
Participants at baseline comprised 12,395 adolescents (M/F: 5,529/6,799; mean age=14.9±0.9) from Austria, Estonia, France, Germany, Hungary, Ireland, Israel, Italy, Romania, Slovenia and Spain. At the 3 and 12 months follow up, participation rates were 87.3% and 79.4%, respectively. Demographic characteristics of participating sites were found to be reasonably representative of their respective national population. Overall response rate of schools was 67.8%. All scales utilised in the study had good to very good internal reliability, as measured by Cronbach’s alpha (BDI-II: 0.864; Z-SAS: 0.805; SDQ: 0.740; WHO-5: 0.799).
SEYLE achieved its objective of recruiting a large representative sample of adolescents within participating European countries. Analysis of SEYLE data will shed light on the effectiveness of important interventions aimed at improving adolescent mental health and well-being, reducing risk-taking and self-destructive behaviour and preventing suicidality.