Table 1

Articles related to interventions for reducing neonatal mortality from neonatal tetanus
S. No. Title of article Name of journal and year of publication Study design Study site Key findings
1. Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes (Review) The Cochrane Collaboration and published in The Cochrane Library Systematic review (Cochrane) India, Bangladesh, Pakistan, Gambia, Nepal, Indonesia Significant reduction was observed in maternal morbidity, neonatal mortality, stillbirths and perinatal mortality as a consequence of implementation of community-based care packages.
Review included 18 cluster-randomized/quasi-randomized trials
2010, Issue 11
2. Tetanus toxoid immunization to reduce mortality from neonatal tetanus International Journal of Epidemiology 2010 Systematic review India, Columbia Immunization of pregnant women or women of childbearing age with at least two doses of tetanus toxoid was estimated to reduce mortality from neonatal tetanus by 94%.
3. Process of neonatal tetanus elimination in Nepal Journal of Public Health 2009 Cross sectional survey Nepal National tetanus toxoid supplemental immunization activities in 2000–2004, raised the proportion of children protected at birth against tetanus to above 80%.
4. Intra- and inter-household differences in antenatal care, delivery practices and postnatal care between last neonatal deaths and last surviving children in a peri-urban area of India J. Biosoc. Sci.2010 Comparative cross sectional India Higher percentage of tetanus toxoid immunization, safer delivery practices, postnatal care, higher maternal age and greater birth spacing were likely to reduce neonatal mortality.
5. Maternal and neonatal tetanus The Lancet 2007 Review paper India, New Guinea, Columbia, Pakistan The proposed packages of interventions include improved antenatal care, tetanus toxoid immunization of mothers, and promotion of hygienic delivery and postpartum cord-care, all of which will directly contribute to prevention of maternal and neonatal tetanus.

Khan et al.

Khan et al. BMC Public Health 2013 13:322   doi:10.1186/1471-2458-13-322

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