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Open Access Highly Accessed Research article

Changes in metabolic profiles after the Great East Japan Earthquake: a retrospective observational study

Masaharu Tsubokura1*, Morihito Takita12*, Tomoko Matsumura1, Kazuo Hara3, Tetsuya Tanimoto1, Kazuhiko Kobayashi4, Tamae Hamaki5, Giichiro Oiso1, Masahiro Kami1, Tadaichi Okawada6 and Hidekiyo Tachiya6

Author Affiliations

1 Division of Social Communication System for Advanced Clinical Research, Institute of Medical Science, University of Tokyo, Tokyo, Japan

2 Baylor Research Institute, Islet Cell Laboratory, Dallas, Texas, USA

3 Department of Metabolic Disease, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

4 Department of Hematology and Oncology, JR Tokyo General Hospital, Tokyo, Japan

5 Department of Hematology and Oncology, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan

6 City Office of Soma, Soma, Fukushima, Japan

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BMC Public Health 2013, 13:267  doi:10.1186/1471-2458-13-267

Published: 23 March 2013

Abstract

Background

A magnitude 9.0 earthquake struck off eastern Japan in March 2011. Many survivors have been living in temporary houses provided by the local government since they lost their houses as a result of the great tsunami (tsunami group) or the expected high-dose radiation resulting from the nuclear accident at the Fukushima Daiichi Nuclear Power Plant (radiation group). The tsunami was more than 9 m high in Soma, Fukushima, which is located 30 km north of the Fukushima Daiichi Nuclear Power Plant and adjacent to the mandatory evacuation area. A health screening program was held for the evacuees in Soma in September 2011. The aim of this study was to compare the metabolic profiles of the evacuees before and after the disaster. We hypothesized that the evacuees would experience deteriorated metabolic status based on previous reports of natural disasters.

Methods

Data on 200 subjects who attended a health screening program in September or October of 2010 (pre-quake) and 2011 (post-quake) were retrospectively reviewed and included in this study. Pre-quake and post-quake results of physical examinations and laboratory tests were compared in the tsunami and radiation groups. A multivariate regression model was used to determine pre-quake predictive factors for elevation of hemoglobin A1c (HbA1c) in the tsunami group.

Results

Significantly higher values of body weight, body mass index, waist circumference, and HbA1c and lower high-density lipoprotein cholesterol levels were found at the post-quake screening when compared with the pre-quake levels (p = 0.004, p = 0.03, p = 0.008, p < 0.001, and p = 0.03, respectively). A significantly higher proportion of subjects in the tsunami group with high HbA1c, defined as ≥5.7%, was observed after the quake (34.3%) than before the quake (14.8%) (p < 0.001). Regional factors, periodic clinic visits, and waist circumference before the quake were identified as predictive factors on multivariate analysis for the deterioration of HbA1c.

Conclusions

Post-quake metabolic variables were impaired compared with pre-quake baseline levels in survivors who were living in temporary houses. A natural disaster could affect metabolic profiles, and careful follow-up for survivors should be planned.

Keywords:
Natural disaster; Health screening; Glycemic control; Lipidemia