Table 1

Endophenotypes under study
Behavioural disinhibition
Endophenotype Abbreviation(s) Assessment
(In)efficient allocation of attentional resources in processing task-relevant cognitive information, indexed by the P300 amplitude of the Event-Related brain Potential of an Electroencephalography P300, ERP, EEG Visual novelty oddball paradigm to elicit P300 ERP response [8-11].
Reward-associated/Risky decision-making skills FRN, P300 Balloon Analogue Risk Task (BART; [11,12]) Personality measures by means of BIS/BAS scales [13], BSSS [14], and I7[15,16].
Stress sensitivity
Endophenotype Abbreviation(s) Assessment
Stress reactivity of the hypothalamic-pituitary-adrenal axis, indexed by cortisol HPA Cortisol responses to laboratory stressors, including public speaking, high speed mathematics, mental arithmetic tasks [17,18].
Stress reactivity of the autonomic nervous system, including blood pressure, heart rate, heart rate variability responses ANS, BP, ECG, HR, HRV ANS responses to laboratory stressors, including public speaking, high speed mathematics, mental arithmetic tasks [17,18].

Huizink et al.

Huizink et al. BMC Public Health 2012 12:350   doi:10.1186/1471-2458-12-350

Open Data