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The efficacy and safety of a nicotine conjugate vaccine (NicVAX®) or placebo co-administered with varenicline (Champix®) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

Philippe HJ Hoogsteder*, Daniel Kotz, Paul I van Spiegel, Wolfgang Viechtbauer, Ruth Brauer, Paul D Kessler, Matthew W Kalnik, Raafat EF Fahim and Onno CP van Schayck

BMC Public Health 2012, 12:1052  doi:10.1186/1471-2458-12-1052