Typical kinetics exhibited by the target-cell limited model with a latent phase predicting the course of an influenza infection within a host. We can see that the target cells (T) are consumed rapidly, with viral titer (V ) peaking shortly thereafter. In this picture, there is approximately a 3.6 h delay between the infectious (I) cells’ peak and that of viral titer. The parameters, (β, k, δ, p, c) = (3.2 × 10-5 ([V] · d)-1, 4.0 d-1, 5.2 d-1, 4.6 × 10-2 [V]/d,5.2 d-1), and initial conditions, (T, E, I, V )t=0 = (4 × 108, 0, 0,7.5 × 102 [V]), where [V] is TCID50/mL of nasal wash are from Table 3 of .
Beauchemin and Handel BMC Public Health 2011 11(Suppl 1):S7 doi:10.1186/1471-2458-11-S1-S7