Sensitivity of cumulative attack rates to epidemiological parameters. Cumulative attack rates were determined for a range of values of R0 (1.2-1.8), latent period (2-4 days), and infectious period (5-7 days) in the presence of pH1N1 vaccination. The range of results observed for varying latent and infectious period lengths are presented for each value of R0. Vaccination began the week of October 26, 2009 and continued for 8 weeks, to obtain the actual coverage levels outlined in Table 2. For a given value of R0, the most steep curves (and highest attack rates in the presence of vaccination) were observed with a latent period of 2 days and infectious period of 5 days, and the least steep curves (lowest attack rates with vaccination) were observed with a latent period of 4 days and infectious period of 7 days.
Conway et al. BMC Public Health 2011 11:932 doi:10.1186/1471-2458-11-932