Email updates

Keep up to date with the latest news and content from BMC Public Health and BioMed Central.

Open Access Research article

The incidence of type 1 diabetes mellitus among 15-34 years aged Lithuanian population: 18-year incidence study based on prospective databases

Rytas Ostrauskas*, Rimantas Žalinkevičius, Nijolė Jurgevičienė, Lina Radzevičienė and Lina Lašaitė

Author Affiliations

Institute of Endocrinology, Lithuanian University of Health Sciences, Eiveniu 2, Kaunas, LT 50009, Lithuania

For all author emails, please log on.

BMC Public Health 2011, 11:813  doi:10.1186/1471-2458-11-813

Published: 19 October 2011

Abstract

Background

The aim of this prospective study was to determine the incidence of type 1 diabetes mellitus in 15-34-year-aged Lithuanian males and females during 1991 - 2008

Methods

A contact system with general practitioners covering 100% of the 15-34-year-aged Lithuanian population was the primary data source. Reports from regional endocrinologists and statistical note-marks of State patient insurance fund served as secondary sources for case ascertainment.

Results

The average age-standardized incidence rate was 8.30 per 100,000 persons per year (95% Poisson distribution confidence interval [CI] 7.90-8.71) during 1991 - 2008 and was statistically significantly higher among males (10.44 per 100,000 persons per year, 95% CI 9.82-11.10) in comparison with females (6.10 per 100,000, 95% CI 5.62-6.62). Male/female rate ratio was 1.71 (95% CI 1.63-1.80). Results of the linear 1991 - 2008 regression model showed that the incidence of Type 1 diabetes in 15-34-year-aged males and females decreased slightly over the time (r = -0.215, p > 0.05).

Conclusions

Our data demonstrated the male predominance in primary incidence of type 1 diabetes mellitus in 15-34-year-aged population in Lithuania. The incidence of type 1 diabetes mellitus in 15-34-year-aged males and females decreased slightly during 1991-2008.