Table 3 |
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Example of diagnostic codes with the highest and lowest positive predictive value (excerpted from additional file 1) |
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Example of diagnostic codes with the HIGHEST positive predictive value (PPV) |
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|
Syndrome |
ICD-9 code |
Diagnostic label |
PPV (95% CI) |
|
|
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|
Fever1 |
82.8 |
Tick-borne rickettsiosis not elsewhere classified |
1.00 (1.00, 1.00) |
|
88.8 |
Other specified arthropod-borne diseases |
1.00 (1.00, 1.00) |
|
|
|
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Gastrointestinal1 |
7.1 |
Giardiasis |
1.00 (1.00, 1.00) |
|
5.9 |
Food poisoning not otherwise specified |
1.00 (1.00, 1.00) |
|
|
|
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Neurological1 |
323.0 |
Encephalitis in viral disease classified elsewhere |
1.00 (1.00, 1.00) |
|
784.3 |
Aphasia |
1.00 (1.00, 1.00) |
|
|
|
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|
Rash1 |
53.8 |
Herpes zoster with unspecified complication |
1.00 (1.00, 1.00) |
|
695.2 |
Erythema nodosum |
1.00 (1.00, 1.00) |
|
|
|
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Respiratory1 |
33.0 |
Bordetella pertussis |
1.00 (1.00, 1.00) |
|
462.9 |
Pharyngitis, acute not otherwise specified |
1.00 (1.00, 1.00) |
|
|
|
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|
ILI large-group2 |
487.0 |
Influenza with pneumonia |
1.00 (1.00, 1.00) |
|
486.0 |
Pneumonia, organism not otherwise specified |
1.00 (1.00, 1.00) |
|
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Example of diagnostic codes with the LOWEST positive predictive value (PPV) |
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|
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|
Syndrome |
ICD-9 code |
Diagnostic label |
PPV (95% CI) |
|
|
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|
Fever1 |
88.0 |
Bartonellosis |
0.00 (0.00, 0.00) |
|
78.2 |
Sweating fever |
0.00 (0.00, 0.00) |
|
|
|
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|
Gastrointestinal1 |
555.0 |
Regional enteritis, small intestine |
0.00 (0.00, 0.00) |
|
1.1 |
Cholera due to Vibrio cholerae El Tor |
0.00 (0.00, 0.00) |
|
|
|
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|
Neurological1 |
323.2 |
Encephalitis in protozoal disease classified elsewhere |
0.00 (0.00, 0.00) |
|
53.0 |
Herpes zoster with meningitis |
0.00 (0.00, 0.00) |
|
|
|
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|
Rash1 |
51.0 |
Cowpox |
0.00 (0.00, 0.00) |
|
55.8 |
Measles complications not otherwise specified |
0.00 (0.00, 0.00) |
|
|
|
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|
Respiratory1 |
20.4 |
Secondary pneumonic plague |
0.00 (0.00, 0.00) |
|
79.8 |
Hantavirus infection |
0.00 (0.00, 0.00) |
|
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|
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|
ILI large-group2 |
490.0 |
Bronchitis not otherwise specified |
0.00 (0.00, 0.00) |
|
465.8 |
Acute upper respiratory infection, other multiple sites |
0.36 (0.08, 0.65) |
|
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1 Syndrome case definitions developed and published by the US Centers for Disease Control and Prevention (CDC) in 2003, and used by the US Department of Defense's Electronic Surveillance System for Early Notification of Community-based Epidemics (ESSENCE). 2 Syndrome case definition developed in the context of the US Department of Defense's Electronic Surveillance System for Early Notification of Community-based Epidemics (ESSENCE). |
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Cadieux et al. BMC Public Health 2011 11:17 doi:10.1186/1471-2458-11-17 |
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