Table 4

Frequency, age-adjusted risk, and risk ratio of the occurrence of lung cancer, identified by hospital discharge records, between baseline and 31 December 2005 by number of categories of adverse childhood experiences (ACEs) and smoking status among 15,365 adults

Relative risk of lung cancer*


N

Hospitalized

with lung cancer | Risk**

Model A

RR (95% CI)

Model B

RR (95% CI)


Categories of ACEs, No.

0

5595

20 | 152.1

1.00 (referent)

1.00 (referent)

1

4030

10 | 103.8

0.73 (0.34, 1.58)

0.67 (0.31-1.45)

2

2447

11 | 195.6

1.48 (0.70, 3.10)

1.29 (0.61-2.74)

3

1428

12 | 574.4

3.10 (1.49, 6.46)

2.46 (1.17-5.19)

4 or 5

1469

  9 | 433.7

2.55 (1.13, 5.74)

2.06 (0.90-4.72)

6, 7, or 8

396

  2 | 347.8

3.18 (0.71, 14.15)

2.14 (0.46-9.89)

P for trend <0.001

P for trend = 0.007

Smoking status

Never

7808

  7 | 58.8

1.00 (referent)

Former

6281

37 | 225.4

4.44 (1.95-10.12)

Current, <20 cig/d

772

  6 | 591.4

10.27 (3.39-31.13)

Current, ≥ 20 cig/d

504

14 | 1662.8

26.97 (10.39-69.98)

Total

15,365

64 | 201.3


ACEs, adverse childhood experiences RR, risk ratio CI, confidence interval

* Hospital discharge diagnosis of lung cancer defined by ICD-9 code 162

** Risk (per 100,000 population) age-standardized to the 2000 Census population for California

Model A adjusted for age, sex, race/ethnicity, education, marital status, financial problems

Model B adjusted for age, sex, race/ethnicity, education, marital status, financial problems, smoking status, parental smoking history. In addition to the RR estimates for ACE score, we show the RR estimates for smoking status from the regression model.

Brown et al. BMC Public Health 2010 10:20   doi:10.1186/1471-2458-10-20

Open Data