BMC Psychiatry

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Open Access Highly Access Research article

Evidence for genetic association of RORB with bipolar disorder

Casey L McGrath1,2, Stephen J Glatt3, Pamela Sklar1, Helen Le-Niculescu4, Ronald Kuczenski5, Alysa E Doyle6, Joseph Biederman6, Eric Mick6, Stephen V Faraone3, Alexander B Niculescu4* and Ming T Tsuang5*

Author Affiliations

1 Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA

2 Department of Biology, Indiana University, Bloomington, IN, USA

3 Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA

4 Laboratory of Neurophenomics, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA

5 Department of Psychiatry, UC San Diego, La Jolla, CA, USA

6 Pediatric Psychopharmacology Unit, Massachusetts General Hospital; Psychiatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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BMC Psychiatry 2009, 9:70 doi:10.1186/1471-244X-9-70

Published: 12 November 2009

Additional files

Additional file 1:

Genotyped SNPs and assay primer sequences. This table lists the SNPs genotyped and includes sequences of the assay primers used for genotyping.

Format: DOC Size: 536KB Download file

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Additional file 2:

Association results for all analyzed RORA and RORB SNPs. This table details the association results for all RORA and RORB SNPs analyzed and includes results from both case-control and family-based samples.

Format: DOC Size: 1.4MB Download file

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Additional file 3:

Association results for age-at-onset quantitative trait analysis. This table contains the results of the quantitative trait association analyses of RORA and RORB SNPs with age-at-onset of bipolar disorder.

Format: DOC Size: 411KB Download file

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Additional file 4:

RORB SNPs associated with bipolar disorder in genome-wide association studies. This table contains the P-values of RORB SNPs associated with bipolar disorder in our study and four genome-wide association analyses.

Format: DOC Size: 32KB Download file

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