Table 2

Severity of the illness at baseline and at 24 months.

Pure Mania

Mixed episode


Baseline

n = 504

24 months

n = 364 (72%)

Baseline

n = 262

24 months

n = 164 (63%)


Consultation (n,%):

Out-patient

352 (70%)

354 (97%)

169 (65%)

156 (95%)

In-patient

152 (30%)

9 (2%)

92 (35%)

7 (4%)

Suicide attempt:

0

461 (91%)*

317 (87%)*

207 (79%)*

121 (74%)*

1

22 (4%)*

32 (9%)*

26 (10%)*

29 (18%)*

>1

10 (2%)*

15 (4%)*

23 (9%)*

14 (9%)*

Substance abuse and dependence (n,%):

Alcohol

128 (25%)

9 (2%)

70 (27%)

7 (4%)

Cannabis

72 (14%)

8 (2%)

28 (11%)

3 (2%)

Other substances

29 (6%)

2 (< 1%)

25 (10%)

0 (0%)


Assessment scales:

YMRS (mean score ± SD)

27.4 ± 8.8*

. (a)

25.3 ± 9.0*

. (a)

CGI (mean score ± SD):

CGI-BP Overall

4.5 ± 1.2

2.4 ± 1.6

4.7 ± 0.8

2.5 ± 1.4

CGI-BP Mania

4.8 ± 0.9*

1.9 ± 1.5

4.6 ± 0.8*

2.0 ± 1.3

CGI-BP Depression

1.4 ± 0.5*

1.5 ± 0.9*

3.9 ± 0.9*

2.1 ± 1.2*

CGI-BP Hallucinations

2.7 ± 1.7

1.4 ± 0.9*

2.5 ± 1.6

1.6 ± 1.1*

Frequency of social activities (n,%):

Never

112 (22%)*

44 (12%)

77 (29%)*

19 (12%)

1 – 4 times

219 (43%)*

150 (41%)

116 (44%)*

91 (55%)

≥ 5 times

171 (34%)*

169 (46%)

69 (26%)*

53 (32%)

Impairment of work activities (n,%):

None

70 (14%)*

175 (48%)*

18 (7%)*

51 (31%)*

Some impairment

406 (81%)*

166 (46%)*

233 (89%)*

106 (65%)*

Satisfaction with life (n,%):

Satisfied

160 (32%)*

276 (76%)*

47 (18%)*

96 (59%)*

Neither satisfied nor dissatisfied

138 (27%)*

68 (19%)*

47 (18%)*

37 (23%)*

Dissatisfied

204 (40%)*

20 (5%)*

166 (63%)*

30 (18%)*


(a)The YMRS scale was not assessed at the T10 visit, at 24 months.

* = There is a significant difference between the Pure Mania and Mixed Episode patient groups, threshold α = 0.05.

Azorin et al. BMC Psychiatry 2009 9:33   doi:10.1186/1471-244X-9-33

Open Data