|
Basic demographic and clinical result on co-variables and putative predictors of diagnostic stability |
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| Putative co-variables of diagnostic stability |
Value |
Number● |
25–75% Percentiles |
|
|
|||
| Alcohol or drug addiction ever present |
Yes |
70% |
|
| Clinical Global Impression Scale (CGI)▲ |
5–7 |
50% |
|
| Civil status, (i.e. ever married) |
Yes |
69% |
|
| Employment at onset |
Yes |
66% |
|
| Global Assessments of Functioning (GAF)▲▲ |
Score |
40 |
(35–45) |
| Poor premorbid social or work adjustment |
Yes |
71% |
|
| Somatic co-morbidity (any somatic illness ever present) |
Yes |
43% |
|
| Treatment response on antipsychotics |
Yes |
95% |
|
|
|
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| Putative predictors of diagnostic stability |
|||
|
|
|||
| Age of first admission |
Year |
25 |
(20–32) |
| Age of onset |
Year |
21 |
(17–30) |
| Duration of first admission |
Days |
37 |
(8–69) |
| Duration of hospitalisation first year of admission |
Days |
107 |
(50–295) |
| Family history of psychiatric disease |
Yes |
81% |
|
| First diagnosis ICD-10 schizophrenia |
Yes |
23% |
|
| First diagnosis ICD-10 schizophrenia spectrum disorder |
Yes |
53% |
|
| Gender |
Men |
63% |
|
| Sct. Louis Criteria for Schizophrenia▲▲▲ |
Yes |
45% |
|
| Year of birth |
Year |
1962 |
(1954–1970) |
|
|
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| Measures of hospitalisation events |
|||
|
|
|||
| Number of hospitalisations |
(#) |
14 |
(8–26) |
| Total duration of hospitalisation |
Years |
3,4 |
(1,7–6,0) |
| Total duration of illness |
Years |
17 |
(8–24) |
| Year of first admission |
Year |
1989 |
(1982–1999) |
|
|
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| Measures of diagnostic stability |
|||
|
|
|||
| Numbers-of-diagnostic-shifts |
(#) |
3 |
(1–6) |
| Numbers-of-diagnostic-spectrum-shifts● |
(#) |
1 |
(0–4) |
| Diagnostic-complexity (numbers-of-unique-diagnoses multiplied with numbers-of-diagnostic-shifts)●● |
(#) |
8 |
(2–22,5) |
| Spectrum-complexity (numbers-of-unique-spectrum-diagnoses multiplied with numbers-of-diagnostic-spectrum shifts)●●● |
(#) |
2 |
(0–9) |
|
●Numbers of shifts between the three spectra assessed, i.e. schizophrenia spectrum, affective disorders and all others. ●●Diagnostic complexity was calculated as the sum of the numbers-of-unique-diagnoses multiplied with numbers-of-diagnostic-shifts ICD-8 and ICD-10, respectively. ●●●Spectrum complexity was calculated as numbers-of-unique-spectrum-diagnoses multiplied with numbers-of-diagnostic-spectrum-shifts for ICD-10 translated ICD-8 and ICD-10. ●Eleven of the 100 subjects in the sample were identified as having possible year of onset before 1969 (the year when the psychiatric register became electronic, no further information was available), these subjects were therefore excluded from analyses. ▲Guy, 1976; CGI scores were collapsed into the severe forms [score 5–7] vs. the milder forms [2-4]. ▲▲ Endicott et al, 1976. ▲▲▲ Feighner et al, 1972. | |||
Jakobsen et al. BMC Psychiatry 2007 7:41 doi:10.1186/1471-244X-7-41 |
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