Table 1

SIGH-SAD Outcome Measures at Randomization and after 1, 2, 3 and 4 weeks of treatment.

Mean SIGH SAD score*

Mean SIGH SAD score As % of randomization score

% Participants in remission (SIGH SAD <9)


Active

Control

Active

Control

p value

Active

Control

p value


Randomization

28.0 ± 5.3

25.1 ± 3.2

-

-

-

-

-

-

Week 1

18.6 ± 7.9

19.0 ± 7.2

67.1 ± 26.7

74.0 ± 22.5

0.527

7.1

11.1

0.999

Week 2

14.9 ± 10.0

17.9 ± 4.9

54.5 ± 36.4

71.7 ± 19.5

0.208

28.6

0.0

0.127

Week 3

11.1 ± 10.1

14.9 ± 4.2

39.0 ± 30.7

54.4 ± 17.9

0.080

42.9

11.1

0.176

Week 4

8.7 ± 8.4

13.4 ± 5.4

29.9 ± 25.4

54.4 ± 21.8

0.027**

57.1

11.1

0.040***


Notes: Observed cases analysis: for active treatment n = 14 and for placebo treatment n = 9. * interaction of time and treatment significant in repeated measures ANOVA as noted in text. ** comparison significant at p ≤ 0.05 by t test. *** comparison significant at p ≤ 0.05 by Fisher's exact test.

Desan et al. BMC Psychiatry 2007 7:38   doi:10.1186/1471-244X-7-38

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