Table 1

Baseline demographic and clinical characteristics
Characteristics N = 624
Age, years, mean (SD) 47.6 (13.8)
Gender, n (%)
Women 408 (65.4)
Ethnicity, n (%)
Caucasian 611 (97.9)
Marital status, n (%)
Married 379 (60.7)
Single 132 (21.1)
Other1 113 (18.1)
Education, n (%)
Illiterate 12 (1.9)
Basic school education 252 (40.4)
High school/higher education 316 (50.6)
Employment status, n (%)
Active 264 (42.3)
Not working (unemployed or sick leave) 148 (23.7)
Other2 212 (34.0)
Patients with medical comorbidity, n (%) 339 (54.3)
Family psychiatric history, n (%) 221 (35.4)
Number of previous episodes, mean (SD) 2.6 (2.5)
Patients with 1st episode, n (%) 280 (44.9)
Age at first episode of depression, mean (SD) 40.5 (14.0)
Current depressive episode:
Length, mean weeks (SD) 13.9 (23.5)
Chronicity ≥2 years, n (%) 38 (6.1)
HAMD-17 total score, mean (SD) 24.6 (5.7)
Residual symptoms, mean (SD)
Core mood3 8.7 (2.3)
Insomnia4 3.9 (1.4)
Anxiety5 6.2 (2.2)
Somatic6 1.1 (0.6)
VAS-overall pain, total score (mean) 41.4 (28.2)
Monotherapy, n (%) 550 (88.1)
SSRI 145 (26.4)
SNRI 387 (70.3)
Tricyclic antidepressants 6 (1.1)
Others 12 (2.2)
Combination of antidepressants, n (%) 74 (11.9)

MDD = Major depressive disorder; SSRI = Selective serotonin reuptake inhibitor; SNRI = Serotonin-norepinephrine reuptake inhibitor; SD = Standard deviation; VAS = Visual Analog Scale; 1Widowed, separated, divorced and other; 2Student, housekeeping, retired, disabled worker; 3depressed mood [Item 1], guilt [Item 2], suicide [Item 3], and anergia/anhedonia [Item 7] of the HAMD-17; 4early [Item 4], middle [Item 5], and late insomnia [Item 6] of the HAMD-17; 5agitation [Item 9], psychic anxiety [Item 10], somatic anxiety [Item 11], and hypochondriasis [Item 15] of the HAMD-17; 6item 13 of the HAMD-17.

Romera et al.

Romera et al. BMC Psychiatry 2013 13:51   doi:10.1186/1471-244X-13-51

Open Data