Table 1

Neuroimaging acquisition sequences
Type Parameters Min
Localizer and calibration 2
3D SPGR T1-weighted, for online placement of VOI and its offline tissue segmentation 256 x 256 matrix; 170 sagittal slices; 1 mm isotropic resolution, no inter-slice gap; TR = 11.3 s; TE = 4.2 ms; flip angle = 20 deg. 7
1H-MRS volume of interest (VOI) Online VOI placement; shimming (values are carried over to each subsequent 1H-MRS acquisition) 6
NAA concentration levels and T2 time constants of NAA PRESS; TR = 3 s; TEs = 80, 120, 180, 350, 600 ms; NEX = 64 25
T2 time constants of water TR = 10 s; TEs = 50, 60, 80, 120, 180, 350, 600, 800, 1000 ms; NEX = 4 20
Diffusion-weighted images TR = 8.5 s; TE 80–90 ms; flip angle = 90 deg; 54 non-collinear diffusion weighting directions, b-factor of 1000 s/mm2; 6 acquisitions, b-factor of ~ 0 s/mm2; 256 x 256 matrix; 260 FOV; 1.02 x 1.02 x 3 mm3 voxels; NEX = 1; acquisition of field maps. 25

Bernier et al.

Bernier et al. BMC Psychiatry 2013 13:264   doi:10.1186/1471-244X-13-264

Open Data