Table 1

Baseline and demographic characteristics
Characteristic LY2140023 SOC p Value*
(N = 130) (N = 131)
Age, years, mean (SD) 38.7 (10.9) 39.5 (12.5) .579
Gender – female, n (%) 45 (34.6) 44 (33.6) .897
Race, n (%) - - .669
  American Indian or Alaska Native 20 (15.4) 18 (13.7) -
  Black/African American 44 (33.8) 39 (29.8) -
  Multiple 1 (0.8) 3 (2.3)
  White 65 (50.0) 71 (54.2) -
Diagnosis, n (%) - - .202
  Catatonic 1 (0.8) 0 (0.0) -
  Disorganized 8 (6.2) 4 (3.1) -
  Paranoid 100 (76.9) 109 (83.2) -
  Residual 7 (5.4) 2 (1.5)
  Undifferentiated 14 (10.8) 16 (12.2) -
Weight, kg, mean (SD) 83.0 (21.5) 82.7 (21.7) .907
Age of first episode, years, mean (SD) 24.6 (8.3) 23.1 (8.5) .148
Episodes in the last 24 months, mean (SD) 1.8 (1.6) 2.0 (2.1) .297
CGI-S, mean (SD) 3.8 (0.7) 3.7 (0.6) .943
PANSS total, mean (SD) 85.6 (14.8) 85.1 (15.8) .788
PANSS positive, mean (SD) 17.6 (4.7) 18.1 (4.8) .355
PANSS negative, mean (SD) 26.2 (4.9) 25.7 (5.2) .403
PANSS general psychopathology, mean (SD) 41.9 (9.1) 41.4 (9.3) .644
Negative Assessment Scale-16, mean (SD) 58.7 (11.0) 57.3 (11.3) .336

Abbreviations: CGI-S Clinical global impressions Severity, n/N Number of patients, PANSS Positive and negative syndrome scale, SD Standard deviation.

Groups: LY2140023, LY2140023 monohydrate, SOC, Standard-of-care.

*P < .05, LY2140023 versus SOC.

Adams et al.

Adams et al. BMC Psychiatry 2013 13:143   doi:10.1186/1471-244X-13-143

Open Data