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Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study

Sean N Hatton12*, Jim Lagopoulos1, Daniel F Hermens1, Sharon L Naismith1, Maxwell R Bennett1 and Ian B Hickie1

Author Affiliations

1 Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, Sydney, NSW, Australia

2 Postal Address: Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Sydney, NSW, 2050, Australia

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BMC Psychiatry 2012, 12:45  doi:10.1186/1471-244X-12-45

Published: 20 May 2012

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Additional file 1::

Linear correlations of anterior insula GMV with clinical/neurocognitive variables controlling for years of education. Description of data: Linear correlations of clinical variables and neurocognitive executive functioning to patient anterior insula GMV, controlling for years of education. Pearson’s r (normal score distribution) or Spearman’s ρ (non-normal score distribution) correlation analysis explored the linear relationship between the left or right anterior insula GMV (corrected for ICV) against patient demographic, clinical variables or z-scores of neuropsychological assessments of executive function (n = 133), controlling for years of education. *p < .05; **p < .01 (2-tailed).

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