Table 1

Medication dose and reasons for discontinuation before and after switching
Before switching After switching
OLZ-RIS (n=162) RIS-OLZ (n=136) OLZ-RIS (n=162) RIS-OLZ (n=136)
Dose (Mean ± SD) 10.1±5.3 4.7±3.0 4.6±3.2 10.9±5.9
Reason for discontinuation (%)a
  Lack of efficacy 41.3 59.1 36.0 34.0
  Intolerability 29.7 31.8 15.7 20.0
  Lack of compliance 19.4 23.5 19.1 16.0
  Patient request 34.8 28.8 19.1 26.0

aMore than one reason allowed.

OLZ-RIS: Patients who switched from olanzapine to risperidone.

RIS-OLZ: Patients who switched from risperidone to olanzapine.

Hong et al.

Hong et al. BMC Psychiatry 2012 12:218   doi:10.1186/1471-244X-12-218

Open Data