Figure 3.

Tie2 mRNA levels and increased brain echogenicity. Serial head US scans were performed on all patients in the first week of life followed by a second one 10 days later and then a third at one month of age. Circulating Tie2 mRNA levels were measured at 3 time points after birth by qRT-PCR as described under 'Materials and Methods" in preterm infants with normal brain US (A) and in preterm infants with increased echogenicity on brain sonography (B). The data was analyzed using ANOVA analysis with repeated measurements.