Table 3

Simulation values and the percentage of detected CD children (sensitivity) with approximately 2% false-positives (= 98% specificity)

(symptomatic) CD

Simulation values*

Sensitivity (95%-CI)

100-Specificity (95%-CI)

PPV


BMI extended delta rule

e2 = 0

f1 = -1.5

g2 = -2.5

30 (20–40)

1.9 (1.3–2.5)

0.85%

BMI delta rule

e1 = 0.5

g1 = -1.5

27 (16–38)

1.9 (1.3–2.5)

0.76%

Slowed growth for BMI rule

e3 = 0

f2 = -2

g3 = -2.5

22 (11–33)

1.8 (1.2–2.4)

0.65%

Conditional weight gain rule

e4 = 0.5

f3 = -2.5

g4 = -0.5 to -1.5

21 (12–30)

1.9 (1.3–2.5)

0.58%


*Table 1 explains the interpretation of the simulation values

van Dommelen et al. BMC Pediatrics 2008 8:35   doi:10.1186/1471-2431-8-35

Open Data