|
Diagnostic work up in correctly (CR) and not correctly referred (NCR) children > 3 years old. |
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| University hospital |
General hospital |
Difference in categories between 2 hospitals (p-value) |
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|
|
||||||
| CR (n = 284) (%) |
NCR (n = 63) (%) |
CR (n = 85) (%) |
NCR (n = 24) (%) |
|||
|
|
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| Routine laboratory investigations |
||||||
| Anemia/infections |
0.4/39.8 |
0.0/25.4 |
1.2/57.6 |
4.2/37.5 |
< 0.01 |
|
| Liver diseases |
22.5/4.2 |
2.8/0.0 |
14.1/21.2 |
8.3/25.0 |
0.03 |
|
| Renal diseases (blood) |
1.4/27.3 |
0.0/17.5 |
0.0/38.8 |
0.0/33.3 |
0.5 |
|
| Celiac disease |
21.1/15.8 |
11.1/3.2 |
49.4/4.7 |
25.0/4.2 |
< 0.01 |
|
| Hypothyroidism |
37.0/3.2 |
2.5/0.0 |
45.9/3.5 |
29.2/8.3 |
0.02 |
|
| Growth hormone deficiency |
35.2 |
9.5 |
45.9 |
25 |
0.02 |
|
| Turner syndrome * |
17.2 |
6.5 |
14.0 |
18.1 |
1.0 |
|
| Renal diseases (urine) |
0.0/19.4 |
0.0/19.0 |
0.0/40.0 |
0.0/29.2 |
< 0.01 |
|
| Combined categories (at least one test category) |
4.9/52.1 |
1.6/39.7 |
18.8/49.4 |
33.3/16.7 |
< 0.01 |
|
| Further and specific diagnostics |
||||||
| Special investigations |
Chromosomal analyses for Turner syndrome* |
26.2 |
6.5 |
26.0 |
0.0 |
0.9 |
| Biopsy** |
2.1 |
0.0 |
5.9 |
0.0 |
0.03 |
|
| Zinc-determination |
0.4 |
0.0 |
0.0 |
0.0 |
0.6 |
|
| Further, more specific tests |
GH-tests |
16.2 |
3.2 |
12.9 |
0.0 |
0.3 |
| Other tests*** |
8.8 |
3.2 |
28.2 |
25.0 |
< 0.01 |
|
|
Percentages of patients with Complete (all elements)/partial (at least one element) evaluation are given (several test categories per patient). CR = Correctly referred; NCR = Not correctly referred * These categories are only applicable to girls. The percentages are therefore calculated only on the female population. **biopsy to rule out celiac disease. *** other tests, like stool examinations, X-rays of the skeleton, ultrasounds of abdomen, hart, kidneys and thyroids, serum levels of steroids, genetic analyses, immunologic tests and allergic tests | ||||||
Grote et al. BMC Pediatrics 2008 8:21 doi:10.1186/1471-2431-8-21 |
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