Table 4

Rates of major neurodevelopmental impairment* detectable at 1 year adjusted age in Epochs 1 and 2.


Epoch 1
Epoch 2


# seen/# survivors (%)
% impaired (95% CI)
# seen/# survivors (%)
% impaired (95% CI)

23 weeks
4/4 (100)
0 (0, 60)
11/13 (85)
73 (39, 94)
24 weeks
22/22 (100)
41 (21, 64)
39/43 (91)
26 (13, 42)
25 weeks
41/43 (95)
15 (6, 29)
36/40 (90)
6 (1, 19)
26 weeks
63/68 (93)
22 (13, 34)
63/75 (85)
11 (5, 22)
27 weeks
57/70 (80)
16 (7, 28)
65/80 (81)
6 (2, 15)
23–27 weeks
187/207 (90)
20 (15, 27)
214/251 (85)
14 (10, 20)

* Major neurodevelopmental impairment in infants seen in our follow up clinic: cerebral palsy, Bayley Scales of Infant Development Mental Development Index >2 SD below the mean, or blindness

Washburn et al. BMC Pediatrics 2007 7:20   doi:10.1186/1471-2431-7-20