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Summary of tests used for different clinical applications |
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| Aim |
Current Reference standard |
Tests |
Advantage over the reference standard |
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| Localisation of infection |
Tc-99 m-DMSA renal scintigraphy |
Clinical features Laboratory-based tests Ultrasound |
All less invasive, no exposure to ionising radiation |
| Detection of reflux |
Micturating cystourethrography (MCUG) |
Ultrasound |
Less invasive, no exposure to ionising radiation |
| Indirect radionuclide cystography |
Single procedure test for reflux and scarring |
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| Prediction of renal scarring |
Follow-up Tc-99 m-DMSA renal scintigraphy |
Clinical features |
Would allow earlier prediction of children at risk of renal scarring |
| Ultrasound |
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| MCUG |
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| Acute DMSA renal scintigraphy |
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| Detection of renal scarring |
Tc-99 m-DMSA renal scintigraphy |
Ultrasound |
Less invasive, no exposure to ionising radiation |
| Intravenous pyelography (IVP) |
Provides a detailed anatomic map, considered essential where surgery is planned. |
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| Radionuclide cystography |
Advocated as a single procedure test for reflux and scarring |
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Westwood et al. BMC Pediatrics 2005 5:2 doi:10.1186/1471-2431-5-2 |
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