|
Clinical outcomes |
||||||
| Placebo group |
N |
LGG group |
N |
P |
Difference between means |
|
|
|
||||||
| Discharge condition |
89 |
90 |
||||
| Early withdrawal |
11 (12.4%) |
8 (8.9%) |
0.609 |
|||
| Treatment failure |
16 (18.0%) |
19 (21.1%) |
0.734 |
|||
| Cessation of diarrhea |
51 (57.3%) |
52 (57.8%) |
0.931 |
|||
| Unresolved diarrhea |
11 (12.45%) |
11 (12.2%) |
0.842 |
|||
| Mean duration of diarrhea (hours)* |
50.4 ± 28.0 |
51 |
58.5 ± 30.2 |
52 |
0.157 |
-19.6 to 3.4 |
| Mean duration of hospitalization (hours)** |
74.7 ± 33.7 |
62 |
81.2 ± 32.6 |
63 |
0.280 |
-18.4 to 5.4 |
| Total stool output (ml/kg) |
195.0 ± 171.9 |
89 |
247.8 ± 180.2 |
90 |
0.047 |
-105.4 to -0.2 |
| Total oral rehydration solution intake (ml/kg) |
236.5 ± 195.6 |
89 |
272.8 ± 188.1 |
90 |
0.208 |
-93.7 to 21.1 |
| Total study formula intake (ml/kg) |
215.5 ± 136.3 |
89 |
231.5 ± 136.6 |
90 |
0.435 |
-56.8 to 24.8 |
| Total energy intake (Kcal/kg)§ |
220.7 ± 140.4 |
89 |
247.4 ± 143.0 |
90 |
0.209 |
-69.1 to 15.7 |
| Total volume of vomitus (ml/kg) |
27.6 ± 45.5 |
89 |
27.4 ± 33.9 |
90 |
0.968 |
-11.8 to 12.2 |
| Total volume of urine (ml/kg) |
81.5 ± 65.2 |
89 |
87.1 ± 69.4 |
90 |
0.579 |
-25.7 to 14.5 |
|
* For patients who ceased diarrhea before 120 hours. ** Patients with treatment failure or early withdrawals are excluded. § Calculated from calories provided by study formula, soft foods, breastmilk, and oral rehydration solution. Values are mean ± SD, n (%), or 95% confidence limits. | ||||||
Salazar-Lindo et al. BMC Pediatrics 2004 4:18 doi:10.1186/1471-2431-4-18 |
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